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The importance for conserving thiol bonds is evident when one understands that incorporation of a cysteine moiety influences the tertiary structure of proteins (e.g., molecule configuration, folding) and can influence effects of certain drugs (e.g., insulin)

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In phase II and III studies, people who took cagrilintide along with semaglutide lost up to 15.7% of their body weight, compared to 5.1% who took a placebo